HEAT SHOCK PROTEIN USES IN VACCINE DEVELOPMENT FOR INFECTIOUS DISEASES AND CANCER
Abstract
Objectives: Heat Shock protein or Heat stress protein (Hsp) are produced by all organisms to overcome heat stress. Henceforth, they are critical controllers of cell multiplication, separation and unequivocally embroiled in the sub-atomic coordination of malignant growth improvement and movement the same number of their customers is settled oncoproteins in numerous tumor types.Methods:Â Curiously, tumor cells are more HSP chaperonage-subordinate than ordinary cells for multiplication and endurance on the grounds that the oncoproteins in malignant growth cells are frequently misfolded and require enlarged chaperonage movement for rectification It also enhances survival rate of organisms. It also acts as immunogen in the host. So it is useful to vaccine development.Results: The production cost of Hsp is low, production method and isolation technique is also easy.Conclusion: If it is combined with DNA vaccine, it will produce long-term immunity.Keywords: Heat shock protein, Heat stress protein, VaccineReferences
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