OVERVIEW ON ANTI-ACNE ACTIVITY OF METHANOL EXTRACT OF DRIED FRUITS OF EMBELIA RIBES

Authors

  • Vijay Kumar Drug Regulatory Affairs, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara-144 001
  • Meenu Bist Department of Pharmacognosy, School of Pharmaceutical Science, Lovely Professional University, Punjab-144 001.

Abstract

Objective: - The present work was undertaken to validate the folk use of traditional Indian medicinal plant in the treatment of skin disorder by using scientific methods.Method: - The anti-acne potential of methanol extract of the fruits of Embelia ribes were evaluated against Propionibacterium acnes, Staphylococcus epidermidis and Malassezia furfur using well diffusion method.Result: - The result showed that drugs were active against all microorganisms. The minimum inhibitory concentration (MIC) value of the E.ribes fruits extract against test S.epidermidis, P. acne, and M. furfur were found to be 500 μg/ml, 600 μg/ml, and 400 μg/ml, respectively.Conclusion: - It was concluded from the study that the plant materials Embelia ribes are effective in acne vulgaris, and hence this can be used in topical anti-acne preparations.Key words: Acne vulgaris, Propionibacterium acnes, Staphylococcus epidermidis, Malassezia furfur 

Author Biographies

Vijay Kumar, Drug Regulatory Affairs, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara-144 001

Drug Regulatory Affairs, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara-144 001

Meenu Bist, Department of Pharmacognosy, School of Pharmaceutical Science, Lovely Professional University, Punjab-144 001.

Department of Pharmacognosy, School of Pharmaceutical Science, Lovely Professional University, Punjab-144 001.

References

. Kapoor, S., Saraf, S., 2011. Topical Herbal Therapies an Alternative and Complementary

Choice to Combat Acne. Research Journal of Medicinal Plant 5, 650–669.

. Pandey, M., Debnath, M., Gupta, S., Chikara, S.K., 2011. Phytomedicine : An ancient approach

turning into future potential source of therapeutics. J. Pharmacogn. Phyther. 3, 27–37.

. Khan, N., Karodi, R., Siddiqui, A., Thube, S., Rub, R., 2012. Development of anti-acne gel

formulation of anthraquinones rich fraction from Rubia cordifolia (Rubiaceae). International

Journal of Applied research in Natural Products 4, 28-36.

. Sinha, P., Srivastava, S., Mishra, N., Yadav, N.P., 2014. New Perspectives on Antiacne Plant

Drugs: Contribution to Modern Therapeutics. Biomed Research International, 1-19.

. Williams, H.C., Dellavalle, R.P., Garner, S., 2012. Acne vulgaris. Lancet. 379, 361–72.

. Yarnell, E., Abascal, K., 2006. Herbal medicine for acne vulgaris. Alternative and

Complementary therapies. 303-309.

. Patel, N.A., Patel, N.J., Patel, R.P., Patel, R.K., 2010. The formulation and evaluation of topical berberine hydrochloride products. Pharmaceutical Technology. 34(1), 60-69.

. Thube, S.A., Patil, M.J., 2012. Traditionally used Indian Medicinal Plants: antibacterial,

antioxidant, antiacne activity and formulation development. Journal of Pharmacy Research 5,

-3130.

. Ghosh, V.K., Nagore, D.H., Kadbhane, K.P., Patil, M.J., 2011. Different approaches of alternative medicines in acne vulgaris treatment. Orient Pharm Exp Med 11. 1–9.

. Sudani R.J., Akbari B.V., G. Vidyasagar., 2011. Pharmacognostical and Preliminary Phytochemical Investigation of Embelia ribes Burm f .International Journal of Pharmaceutical & Biological Archives. 2(2). 648-651.

. Choudhary, G.P., 2012. Anthelmintic activity of fruits of Embelia ribes Burm. International

Journal of Pharmaceutical and Chemical Sciences 1, 1336-1337.

. Jeong - Hyun, L., Lee, J., 2010. Chemical composition and antifungal activity of plant essential oils against Malassezia furfur. Korean Journal of Microbiology and Biotechnology 38, 315-321.

. Sirivan, A., Rith, W., Sujimon, T., Panida, V., Paisarn, K., Prapan, S., Nijsiri, R., 2008. The

development of antiacne products from Eucalyptus globulus and Psidium guajava oil. Journal

of Health Research 22, 109-113.

. Chee, H.Y., Lee, M.H., 2009. In vitro activity of celery essential oil against Malassezia furfur. Journal of Microbiology 37, 67-68.

. Choi. J.S., Bae, H.J., Kim, S.J., Choi, I.S., 2011. In vitro antibacterial and anti-inflammatory

Properties of seaweed extracts against acne inducing bacteria, Propionibacterium acnes.

Journal of Environmental Biology 32, 313-318.

. Zu, Y., Yu, H., Liang, L., Fu, Y., Efferth, T., Liu, X., Wu, N., 2010. Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer Cells 15, 3205-3206.

Downloads

Published

2018-07-01

How to Cite

Kumar, V., & Bist, M. (2018). OVERVIEW ON ANTI-ACNE ACTIVITY OF METHANOL EXTRACT OF DRIED FRUITS OF EMBELIA RIBES. Innoriginal: International Journal of Sciences, 44–46. Retrieved from https://innoriginal.com/index.php/iijs/article/view/186

Issue

Section

RESEARCH ARTICLE