NATIVE SPECTROFLUORIMETRIC DETERMINATION OF AMPROLIUM IN BULK AND PHARMACEUTICAL FORMULATION
Abstract
Objective: The manuscript discussed the application of a simple, accurate and precise spectrofluorimetric method for determination of amprolium in bulk and pharmaceutical formulation.Method: The emission was measured at 320 nm after excitation at 262 nm. Several parameters were optimized to get the most sensitive and reproducible results.Results: The following analytical parameters: limit of detection, limit of quantitation, accuracy, precision and linearity ranges of the method were determined. Statistically, there is no significant difference between the proposed and the reported method.Conclusion: this method can be used for determination of amprolium in bulk and pharmaceutical formulation.Keywords: Amprolium; Native fluorescence, pharmaceutical dosage formReferences
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