Uttam Borah, Biswajit Dash, Padmanath Pegu, Arindam Sarkar, Hrishav Vardwaj, Parag Kumar Sarma


Tablet swigging trouble essentially influences the geriatric and paediatric populaces though unpalatable taste of medications prompts persistent resistance. Swallowing issues additionally are regular in youthful people in light of their immature strong and sensory systems.

Quick Dissolving tablets  are one of the productive aftereffects of ceaseless mechanical progressions in the pharmaceutical business. Fast dissolving tablets assume a noteworthy part in enhancing the patient's consistence. An assortment of medications can be managed as FD tablets as they give the benefit of the fluid drug in the strong planning. These novel sorts of measurements shapes have discovered acknowledgment among the geriatric, paediatric and dysphasic patients.

Quick Dissolving Tablet is a tablet that breaks down or crumbles in the oral cavity without the need of water or biting. It has been produced for oral organization, likewise called as quick liquefy, quick melts, permeable tablets or quick deteriorating or orally crumbling tablets. Mouth dissolving tablets have been defined for paediatric, geriatric, and laid up patients and for dynamic patients who are occupied and voyaging and might not approach water. Such tablets promptly break up or deteriorate in the salivation for the most part inside <60 seconds.

Quick dissolving tablets can be set up by different regular techniques like direct pressure, wet granulation, shaping, splash drying, solidify drying, Cotton Candy Process and sublimation. In 1986, the primary lyophilized quick dissolving innovation Zydis® was presented and a few advancements are as yet making strides.


Keywords: Fast dissolving tablets, Manufacturing approaches, Limitations and advantages, Future prospects and research trends. 

Full Text:



Cheng R, Guo X, Burusid B, Couch R.A review of fast dissolving tablets. Pharm Tech, (North America). June, 2000; 52-58.

Bi Y, Sunada H, Yonezawa Y, Dayo K, Otsuka A, Iida K. Preparation and evaluation of compressed tablet rapidly disintegrating in oral cavity. Chem Pharm Bull (Tokyo)1996; 44:2121-2127.

Quick dissolving tablets. http:/www.biospace.com. 27 may, 2001.

Fu Y, Yang S, Jeong SH, Kimura S, Park K. Orally fast disintegrating tablets: Developments, technologies, taste-masking and clinical studies. Crit Rev Ther Drug Carrier Sys 2004; 21:433-76.

Suresh B, Rajendar K, Mitta P, Ramesh G, Yamsani MR. Orodispersible tablets: An overview. Asian Journal of pharmaceutics-2008; 2(1): 2-11.

Gohel M, Patel M, Amin A, Agarwal R, Dave R, Bariya N. Formulation design and optimization of mouth dissolving tablets of nimesulide using vacuum drying technique. AAPS Pharm Sci Tech 2004; 5(3):10-15.

Panigrahi D, Baghel S, Mishra B. Mouth dissolving tablet: An overview of preparation techniques, evalution and patented technologies. Journal of pharmaceutical research. July 2005; 4(3): 33-38

Indurwade N.H.et al., “Novel approach – Fast Dissolving Tablets , Indian drugs., August 2002 ;39(8):405-409.

Velmurugan S, Vinushitha S. Oral disintegrating tablets:An overview. International Journal Chem Pharma Sci. 2010;1(2):1-12.

Kaur T, Gill B, Kumar S, Gupta GD. Mouth dissolving tablets: a novel approach to drug delivery. Int J Curr Pharm Res 2011;1:1-7.

Patel TS, Sengupta M. Fast dissolving tablet technology. World J Pharm Sci 2013;2:485-508.

Kumari S., Visht S., Sharma P.K., Yadav R.K., (2010)., Fast dissolving Drug delivery system : Review Article; Journal of Pharmacy Research 3(6).,1444-1449.

Bhowmik D, B. Chiranjib, Kant K, Pankaj, R. Margret C. Fast Dissolving Tablet: An Overview. Journal of Chemical and Pharmaceutical Research, 2009, 1(1): 163-177.

Sunita K, Visht S, Sharma PK, Yadav RK. Fast dissolving Drug delivery system: Review Article. Journal of Pharmacy Research 2010, 3(6), 1444-1449.

Sahoo S, Mishra B, Biswal P.K, Panda O, Mahapatra SK, Jana GK. Fast Dissolving Tablet: As A Potential Drug Delivery System. Drug Invention Today 2010,2(2),130-133.

Corveleyn S. and Remon JP. Freeze-Dried Disintegrating Tablets. US patent no. US6 010719. 2000.

Sanket K, Shiv KG. Fast dissolving tablets (: current status, new market opportunities, recent advances in manufacturing technologies and future prospects. Int J Pharm Pharm Sci 2014; 6(7): 22-35.


  • There are currently no refbacks.

Innoriginal: International Journal of Sciences (ISSN: 2349-7041)


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.