Arun Raj R


Objective: To formulate and evaluate meloxicam loaded nanoemulgel for topical drug delivery.

Methods: Nanoemulsion is prepared by spontaneous emulsification technique.  Nanoemulgel is prepared by adding nanoemulsion in to the gel matrix. Characterization of meloxicam loaded nanoemulgel were performed.

Results: The nanoemulgel was evaluated for clarity, homogenicity, pH, viscosity, percentage drug entrapment and In vitro drug release study. The results of the formulation was found to be satisfactory. The drug content was within acceptable range. The drug release mechanism from the tablets was found to be non fickian transport kind of diffusion.

Conclusion: Meloxicam nanoemulgel can be effectively used for topical drug delivery.

Keywords: Meloxicam, Nanoemulsion, Nanoemulgel, spontaneous emulsification.

Full Text:



Patrick S. Doyle, Ankur gupta, H. Barak Eral, T. Alan Hattona. Nanoemulsion: Formulation Properties and Application. Royal society of chemistry. 2016; 12: 2826-2841.

Kalpana Basera, Ganesh Bhatt, Preeti Kothiyal and Pooja Gupta. Nanoemulgel: A Formulation Approach for Topical Delivery of Hydrophobic Drugs. World Journal of Pharmacy and Pharmaceutical Sciences. 2015; 4(10): 1871-1886.

Arun Raj R, Nandkishore K. Formulation and Evaluation of Meloxicam Crystals Using Spherical Crystallization for Solubility Enhancement. Res Rev A J Drug Formul Dev Prod. 2016;3(2):15–35.

Navneet Sharma,Shardendu Mishra. Preparation and Optimization of Nanoemulsion for Targeting Drug Delivery. International Journal for Drug Development and research. 2013; 5(4): 37-48.

S.Sampathy,S.K. Mankala, Nanoemulsion Based Hydrogels For Itraconazole For Transungual Drug Delivery. Journal for Scientific and Industrial Research. 2015; 74: 88-92.

Asiya Mahtab, Mohammed Anwar, Neha Mallick, Zrien Naz, Gaurav K. Jain and Farhan J. Ahmad, Transungual Delivery of Ketoconazole Nanoemulgel for the Effective Management of Onychomycosis. AAPS PharmSciTech. 2016; 17(6): 1477-1490.

Jilby Saju, Arun Raj R. Formulation and Evaluation of Lamotrigine Nanoparticles Incorporated In-Situ Gel for Epilepsy. Int J Pharm Pharm Res. 2018;13(4):177–94.

Arun Raj R. Formulation evaluation and in vitro permeation studies of transdermal nifedipine from matrix type patches. Int J Pharm Pharm Sci. 2014;6(1):185–8.


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.