STUDY OF FC RECEPTOR-LIKE PROTEIN 3 AND ITS BINDING EFFICIENCY WITH HERBAL AND ALLOPATHIC ANTIBIOTICS

Tamizhazhagan V

Abstract


This present study aimed to determine the effect of drug (herbal and allopathic) on the FCRL3. FCRL3 protein sequence was collected from Uni-prot, protein sequence data base and submitted to the SIB- BLAST. The multiple sequence alignment was performed by comparing FCRL3. The protein sequence of Human was compared with domestic duck, Wild Yak, Black flying fox, American mink by using CLUSTAL W2. The secondary structure was determined by using CFSSP. The composition of amino acids was determined by using Protparam. The tertiary structure of FcRL 3 was predicted by using CPH modeling server and visualized through Rasmol. Ramachandran plot was performed for FCRL3 using Rampage software. The active sites were predicted by CASTp. The docking of FCRL3 with selected herbal Acetaminophen and Allopathic methimazole was performed by Hex 6.3.


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This work is licensed under a Creative Commons Attribution 4.0 International License.