STUDIES ON THE IMPACT OF MEDICINAL PLANTS IN RELATION TO MALARIA VECTOR CONTROL AGAINST ANOPHELES STEPHENSI

Bharanitharan Bharani, Muthulingam N, Senthilmurugan S, Dhanasekaran A, Jeyasankar A, Barbara Sawicka

Abstract


The present study phytochemical screening and mosquitocidal activity of three different medicinal plants, Sesamum indicum, Pungamia pinnata, and Croton bonplandionum extracts. The methanol extract of leaf samples were used for the phytochemical analysis to find out the phytochemical constituents in the plants. The main objective of the research work was check the presence or absence of the phytochemical chemicals in all the selected medicinal plants. Phytochemical analysis of these plants confirm the presence of various phytochemicals like alkaloids, flavonoids, saponins, steroids, tannins, terpenoids, tri-terpenoids, anthraquinones, amino acid, phenol, glycosides, carbohydrate, protein and phytosteroids. The highest larvicidal activity of S. indicum methanol extract with LC50/LC95 values were 108.55/230.57 ppm, followed by P. pinnata were 143.59/305.52 ppm, and C. bonplandionum were 154.51/319.01 ppm, respectively. Further, maximum repellent activity of methanol extract showing 100% protection up to 160 min was tested against An. stephensi. However, much scope for further systematic research in screening Tamilnadu medicinal plants for these phytochemicals and assessing their potential in protecting against different types of mosquito diseases.  

Keywords: Sesamum indicum, Pungamia pinnata, and Croton bonplandionum, phytochemical, mosquitocidal


Full Text:

PDF

References


Jayaprasad, B., Sharavanan, S., Veerakumar, K. Effect of Chloroxylonswietenia Dc bark extracts against Culexquinquefasciatus, Aedesaegyptiand Anopheles stephensi larvae. Parasitol.Res.2015; 114: 4219-4223.

Panneerselvam, C., Murugan, K., Kovendan, K., Mahesh Kumar, P., Subramaniam, J. Mosquito larvicidal and pupicidal activity of Euphorbia hirta Linn. (Family: Euphorbiaceae) and Bacillus sphaericus against Anopheles stephensi Liston. (Diptera: Culicidae). Asia. Pac. J. Trop. Med.2013; 102-109.

WHO.Malaria. Fact sheet December. WHO Press2014.

WHO. Malaria.Fact sheet December 2015; 9.

Baranitharan, M., Dhanasekaran, S., Mahesh Babu, S., Sridhar, N.Larcidal activity of CrotonsparciflorusMorong (Euphorbiaceae) leaf extract against three vector mosquitoes. Scien.Park.Res. J.2014; 1: 1-7.

Savithramma, N., LingaRao, M.,Suhrulatha, D. Screening of Medicinal Plants for Secondary Metabolites. Middle-East. J. Sci. Res. 2011; 8: 579-584

Baranitharan, M., Dhanasekaran, S., Murugan, K., Kovendan, K., Gokulakrishnan, J., Benelli, G. Coleus aromaticusleaf extract fractions: A source ofnovelovicides, larvicides and repellents againstAnopheles, Aedesand Culexmosquito vectors?.Proc. Safe. Environ. Prot. 2017; 106: 23-33.http:// dx.doi.org/ 10.1016/j.psep.2016.12.003.

Verpoorte, R.Chemodiversity and theBiological Role of Secondary metabolites, somethoughts for selecting plant material for drugdevelopment. Proc. Phytochem. Soc. Europe, Kluwer Publishers. 1998; 43: 11-24.

Baranitharan, M., Dhanasekaran, S., Murugan, K., Kovendan, K., Gokulakrishnan, J. Chemical composition and laboratory investigation of Melissa officinalisessential oil against humanmalarial vector mosquito, Anopheles stephensiL. (Diptera: Culicidae). J. Coast.Life.Med.2016; 4: 969-973.

Satyavati, G.V., Gupta, A.K.,Tandon, N. Medicinal plants of India, India. Counc.Med. Res.1987; New Delhi, India.

Nahak, G.,Sahu, R.K.In vitro antioxidativeacitivity of Azadirachtaindica and Meliaazedarach leaves by DPPH scavenging assay. J. Am. Sci. 2010; 6: 123-128.

Baranitharan, M., and Dhanasekaran, S. Mosquito larvicidal properties of Commiphoracaudata (Wight &Arn.)(Bursaceae) against Aedesaegypti(Linn.), Anopheles stephensi(Liston),Culexquinquefasciatus(Say).Int. J.Curr.Microbiol.App. Sci. 2014; 3: 262-268.

Charuarorachugh, Sanjeev Mehta,HeenaDua. Phytochemical screening and evaluation of biological activities ofsome medicinal plants of Phagwara, Punjab. Asia. J. Chemist. 2012; 24: 5903-5905.

Kokate, C.K. Practical Pharmacognosy, 4th edition, VallabhPrakashan, New Delhi, 1994; 4-29.

Sathish Kumar, M., Selvakumar, S., Rao, M.R.K.,Anbuselvi, S. Preliminary phytochemical analysis of Dodonaeaviscosaleaves. Asia. J. Plant.Sci. Res. 2013; 3: 43-46.

WHO. Report of the WHO informal consultation on the evaluation and testing of insecticides.CTD/WHOPES/IC/96. 1. Giveaway: Control of Tropical Diseases Division 1996.

Abbott, W.S. A method of computing the effectiveness of an insecticide.J. Eco.Entomol.1925; 18: 265- 267.

WHO.Guidelines for efficacy testing of mosquito repellents for human skin.WHO, Geneva, WHO/HTM/NTD/WHOPES/4, 2009.

Finney, D.J. 1971. A statistical treatment of the sigmoid response curve. In: Probit analysis. CambridgeUniversity Press, London, 1971; pp 633.

Vinha, A.F., Soares, M.O., et al. Phytochemical characterization and radical scavenging activity of aqueous extracts of medicinal plants from Portugal. In: Europea. J. Med. Plan.2012; 2: 335-347.

Marinkovic, N., Vitale, K., Holcer, N.J., Dzakula, A., Pavic, T. Management of hazardous medical waste in Croatia. Waste.Manag. 2008; 28: 1049–1056.

Sayyah, M., Hadidi, N., Kamalinejad, M. Analgesic and anti-inflammatory activity of Lactuca sativa seed extract in rats. J.Ethnopharmacol. 2004; 92: 325–329.

Nyarko, A.A., and Addy, M.E. Effectsof aqueous extract of Adeniacissampeloideson blood pressure andserum analyte of hypertensive patients. In: Phytotherap. Res. 1990; 4: 25-28.

Pal, A. Biotechnology;Secondary Metabolites; Plants andMicrobes. Science Publishers, Portland, 2007.

Baranitharan, M., Dhanasekaran, S., Mahesh Babu, S., Sridhar, N., Krishnappa, K. Larvicidal activity of Coleus aromaticusbenth (Lamiaceae) leaf extracts against three vector mosquitoes. Int. J. Res. Bio. Sci. 2014; 4: 55-59.

Baranitharan, M., Dhanasekaran, S., Gokulakrishnan, J., Krishnappa, K., Deepa, J. Mosquito larvicidal properties of Sesanumindicum L. against Aedesaegypti (Linn.), Anopheles stephensi (Liston), Culexquinquefasciatus (Say) (Diptera: Culicidae). Lif. Sci.Archi. 2015; 1: 72-77.

Baranitharan, M., Dhanasekaran, S., Gokulakrishnan, J., Mahesh Babu, S., Thushimenan, S. Nagapattinam medicinal plants against the dengue fever mosquito, Aedesaegypti. Int. J.Mosq.Res.2016; 3: 29-34.

Baranitharan, M., Dhanasekaran, S., Murugan, K., Kovendan, K., Gokulakrishnan, J., Jeyasankar, A.Experimental investigations of Nagapattinam indigenous medicinal plant extracts against dengue, malaria and filarial disease. Int. J. Zool. Appl.Biosci.2017; 2: 155-161.

Gokulakrishnan, J., Baranitharan, M., Dhanasekaran, S., Deepa, J., Baluselvakumar, Thushimenan, S. Laboratory evaluation of Pedalium murex L. extracts on the South East India disease vector mosquitoes (Diptera: Culicidae). Int. J. Zool. Appl.Biosci.2016; 1: 7-14.

Baranitharan, M., and Dhanasekaran, S. Evaluation of larvicidal activity of Ageratinaadinophora(Spreng)King&H.Rob against Culexquinquefasciatus(Say). Int. J.Pharmaceu. Biol. Archie.2014; 5: 120-125.

Dhanasekaran, S., Krishnappa, K., Anandan, A., and Elumalai, K.J.Larvicidal, ovicidal and repellent activity of selected indigenous medicinal plants against malarial vector Anopheles stephensi (Liston), dengue vector Aedesaegypti (Linn.), Japanese encephalitis vector, Culextritaeniorynchus (Giles.) (Diptera: Culicidae). Agri. Technol.2013; 9: 29-47.

Deepa, J., Gokulakrishnan, J., Baranitharan, M. Effect of plant essential oils on the important mosquito vector, Culexquinquefasciatus(Say). Int. J. Adv. Res. Biol. Sci.2015; 2: 58-61.

Elumalai, K., Dhanasekaran, S., Krishnappa, K.Larvicidal activity of Saponin isolated from Gymnemasylvestre R. Br. (Asclepiadaceae) against Japanese Encephalitis vector, Culextritaeniorhynchus Giles (Diptera: Culicidae). Eur. Rev. Med.Pharmacol.Sci.2013; 17: 1404-1410.

Baranitharan, M.,Dhanasekaran, S., Jeyasankar, A., Arivoli, S., Gokulakrishnan, J. Studies on mossquitocidal activity of Ficusracemosa L. extracts. World. J. Pharmaceu. Lif.Sci. 2016; 2: 199-208.

Mukandiwa, L., NicolaasEloff, J., Naidoo, V. Repellent and mosquitocidal effects of leaf extracts of Clausenaanisata against the Aedesaegyptimosquito (Diptera: Culicidae). Parasitol.Res.2016; DOI 10.1007/s11356-016-6318-9.

Krishnappa, K., and Elumalai,K. Mosquitocidal activity of indigenenous plants of Western Ghats, Achrassapota Linn. (Sapotaceae) and Cassia auriculata L. (Fabaceae) against a common malarial vector, Anopheles stephensi Liston (Culicidae: Diptera). J. Coast.Life.Med.2014; 2: 402-410..


Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.